Oncology News
| Jul 29, 2010 – SOURCE: European Journal of Surgical Oncology (EJSO) | |||
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The impact of young age on breast cancer outcome | |
| AIMS: We conducted a retrospective analysis in order to evaluate the impact of age on women aged less than 35 years affected by breast cancer. MATERIALS AND METHODS: Between January 1972 and December 2006, 346 patients aged less than 35 years underwent ad | |||
| Jul 29, 2010 – SOURCE: Gynecological Endocrinology | |||
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Gynaecologic challenging issues in the management of BRCA mutation carriers: oral contraceptives, prophylactic salpingo-oophorectomy and hormone replacement therapy | |
| BRCA1 and BRCA2 mutation carriers have a 54-85% and 45% lifetime risk of developing breast cancer, respectively, and a 18-60% and 11-27% lifetime risk of developing ovarian cancer, respectively. Oral contraceptives (OCs) significantly reduce the risk of o | |||
| Jul 29, 2010 – SOURCE: Current Opinion in Gastroenterology | |||
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Pancreatic surgery | |
| PURPOSE OF REVIEW: To summarize published research on pancreatic surgery over the past year. RECENT FINDINGS: Improvements in the treatment of patients with acute gallstone pancreatitis with regards to the timing of ERCP and cholecystectomy as well as man | |||
| Jul 29, 2010 – SOURCE: Cancer Genetics and Cytogenetics | |||
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Deletion mapping of chromosome region 12q13-24 in colorectal cancer | |
| Colorectal cancer is one of the most common cancers in the world. Colorectal cancer develops after a long and multistep process of carcinogenesis. Inactivation of tumor suppressor genes is among the most important steps in development of colorectal cancer | |||
| Jul 29, 2010 – SOURCE: Clinical Oncology | |||
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Efficacy and Tolerability of Limited Field Radiotherapy with Concurrent Capecitabine in Locally Advanced Pancreatic Cancer | |
| AIMS: Patients with locally advanced pancreatic cancer (LAPC) are most commonly managed with chemotherapy or concurrent chemoradiotherapy (CRT), which may or may not include non-involved regional lymph nodes in the clinical target volume. We present our r | |||
| Jul 29, 2010 – SOURCE: Cancer Science | |||
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Clinicopathological significance and prognostic value of leukemia-related protein 16 expression in invasive ductal breast carcinoma | |
| To explore the expression of leukemia-related protein 16 (LRP16) in invasive ductal breast carcinoma and analyze its correlation with clinicopathological feature and prognosis, immunohistochemistry was performed on 100 cases of invasive ductal breast carc | |||
| Jul 29, 2010 – SOURCE: Cancer | |||
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The prognostic value of c-Kit, K-ras codon 12, and p53 codon 72 mutations in Egyptian patients with stage II colorectal cancer | |
| BACKGROUND:: The prognosis for patients with colorectal cancer (CRC) depends mainly on standard clinicopathologic factors. However, patients with similar disease characteristics exhibit various outcomes, especially in stage II. Therefore, the identificati | |||
| Jul 29, 2010 – SOURCE: Gastroenterology | |||
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The Presence of Large Serrated Polyps Increases Risk for Colorectal Cancer | |
| BACKGROUND&AIMS:: There is evidence that serrated polyps (serrated adenomas and hyperplastic polyps) have different malignant potential than traditional adenomas. We used a colonoscopy database to determine the association between the presence of serrated | |||
| Jul 29, 2010 – SOURCE: Gastrointestinal Endoscopy | |||
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Prevalence and risk of colorectal neoplasms in asymptomatic, average-risk screenees 40 to 49 years of age | |
| BACKGROUND: A paucity of information exists regarding colorectal neoplasm in asymptomatic, average-risk individuals 40 to 49 years of age. OBJECTIVE: To evaluate the prevalence and risk factors of colorectal neoplasms in those in their 40s. DESIGN: Cross- | |||
| Jul 29, 2010 – SOURCE: European Journal of Cancer | |||
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FGFR4 transmembrane domain polymorphism and cancer risk: A meta-analysis including 8555 subjects | |
| Fibroblast growth factor receptor 4 (FGFR4), belonging to the receptor tyrosine kinase family, is involved in cancer initiation and progression. The FGFR4 Gly388Arg polymorphism in the transmembrane domain of the receptor was shown to contribute to geneti | |||
