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Oncology News

  Aug 26, 2010 – SOURCE: Chemotherapy
Doctor's Guide News Effect of Vitamin C on Lipidperoxidation and Antioxidant Status in Tamoxifen-Treated Breast Cancer Patients
Background: Vitamin C is a water-soluble chain-breaking antioxidant that has beneficial effects on lipid-metabolizing enzymes. In the present study, the level of thiobarbituric acid (TBA) substances and antioxidant enzymes such as catalase, superoxide dis
 
  Aug 26, 2010 – SOURCE: Journal of Gastroenterology
Doctor's Guide News Evaluation of new subclassification of type V(I) pit pattern for determining the depth and type of invasion of colorectal neoplasm
BACKGROUND: Colorectal neoplasms with a type V(I) pit pattern include various lesions, such as adenomas, intramucosal cancers, and submucosal carcinomas. METHODS: We analyzed 96 colorectal neoplasms with a type V(I) pit pattern and identified six differen
 
  Aug 26, 2010 – SOURCE: DGNews
Doctor's Guide News New Nuclear Breast Imaging Technologies Associated With Higher Cancer Risks
OAK BROOK, Ill -- August 26, 2010 -- Some nuclear-based breast imaging exams may increase a woman’s risk of developing radiation-induced cancer, according to a special report appearing early online and in the October print issue of the journal Radiol
 
  Aug 26, 2010 – SOURCE: European Journal of Surgical Oncology (EJSO)
Doctor's Guide News Preoperative cytological and histological diagnosis of breast lesions: A critical review
BACKGROUND: Non-operative pathology diagnoses constitute an essential part of the work-up of breast lesions. With fine needle aspiration (FNA) and core needle biopsy (CNB) both having unique advantages, there is an increasing acceptance of CNB. This paper
 
  Aug 26, 2010 – SOURCE: European Journal of Cancer
Doctor's Guide News Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy
BACKGROUND: NGR-hTNF consists of human tumour necrosis factor (hTNF) fused with the tumour-homing peptide Asp-Gly-Arg (NGR), which is able to selectively bind an aminopeptidase N overexpressed on tumour blood vessels. Preclinical antitumour activity was o
 
  Aug 26, 2010 – SOURCE: European Journal of Nuclear Medicine and Molecular Imaging
Doctor's Guide News (18)F-FDG PET and biomarkers for tumour angiogenesis in early breast cancer
PURPOSE: Tumour angiogenesis is an independent and strong prognostic factor in early breast carcinoma. We performed this study to investigate the ability of (18)F-FDG to detect angiogenesis in early breast carcinoma using PET/CT. METHODS: Twenty consecuti
 
  Aug 26, 2010 – SOURCE: BMC Cancer
Doctor's Guide News Final results of a phase I/II pilot study of capecitabine with or without vinorelbine after sequential dose-dense epirubicin and paclitaxel in high-risk early breast cancer
ABSTRACT: BACKGROUND: The integration of the non-cross-resistant chemotherapeutic agents capecitabine and vinorelbine into an intensified dose-dense sequential anthracycline- and taxane-containing regimen in high-risk early breast cancer (EBC) could impro
 
  Aug 26, 2010 – SOURCE: European Journal of Surgical Oncology (EJSO)
Doctor's Guide News Modified core wash cytology (CWC), an asset in the diagnostic work-up of breast lesions
AIM: A quick and reliable preliminary diagnosis is essential in the management of a same-day breast clinic. In a preclinical study we developed an alternative method of core wash cytology (CWC). This study is an evaluation of this new CWC method introduce
 
  Aug 26, 2010 – SOURCE: Familial Cancer
Doctor's Guide News Relationship of BRCA1 and BRCA2 mutations with cancer burden in the family and tumor incidence
The aim of the present study is to analyze the relationship of the incidence of mutations in the two major genes BRCA1 and BRCA2 conferring risk of breast cancer (BC) and ovarian cancer (OC) with the cancer burden in families and with the presence and age
 
  Aug 26, 2010 – SOURCE: Gastroenterology
Doctor's Guide News Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias
BACKGROUND&AIMS:: Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) occurs during microsatellite instability (MSI) that is not associated with major defects in DNA mismatch repair (MMR) but rather the reduced (heterogenous) e